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Multiple Sclerosis
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Methylprednisolone treatment in multiple sclerosis: effect of treatment, pharmacokinetics, future

OR Hommes

Institute of Neurology, University Hospital Nijmegan

F Barkhof

Department of Radiology, Academic Hospital, Free University Amsterdam

PJH Jongen

Institute of Neurology, University Hospital Nijmegan

STFM Frequin

Department of Neurology, Antonius Hospital, Nieuwegein, the Netherlands

High dose intravenous methylprednisolone treatment is effective and safe in the treatment of relapses in multiple sclerosis, but the long term effects are unclear. Pharmacokinetics are almost unknown, but may be very important for the understanding of the clinical and paraclinical effects. In view of what is known now, IVMP should have a prominent place in basic and clinical MS research.

Key Words: methylprednisolone • pharmacokinetics • future

Multiple Sclerosis, Vol. 1, No. 6, 327-328 (1996)
DOI: 10.1177/135245859600100607


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