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Multiple Sclerosis
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*Multiple Sclerosis
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The pathogenesis of multiple sclerosis: is it really a primary inflammatory process?

F G Maggs

University Department of Neurology, Radcliffe Infirmary, Woodstock Road, Oxford, OX2 6HE, UK, fgmaggs{at}doctors.org.uk

J Palace

University Department of Neurology, Radcliffe Infirmary, Woodstock Road, Oxford, OX2 6HE, UK

The patho genesis of multiple sclerosis (MS) remains unknown. A lthough inflammation, demyelination and axonal injury are all involved, the primary patho genic process is not clear. In this paper we challenge the hypothesis that MS is a primary inflammatory condition, and suggest that axonal damage may occur independently.

Key Words: aetiology • axon • inflammation • multiple sclerosis

Multiple Sclerosis, Vol. 10, No. 3, 326-329 (2004)
DOI: 10.1191/1352458504ms1019rr
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[Abstract] [Full Text] [PDF]


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