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Multiple Sclerosis
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Multiple sclerosis and celiac disease: is there an increased risk?

S Salvatore

Clinica Pediatrica, Università dell’Insubria, Varese, Italy, silvisa{at}tin.it

S Finazzi

Laboratorio di Analisi, Ospedale di Legnano, Italy

A Ghezzi

Centro Studi, Sclerosi Multipla, Ospedale di Gallarate, Italy

A Tosi

Clinica Pediatrica, Università dell’Insubria, Varese, Italy

A Barassi

Dipartimento di Biochimica, Università dell’Insubria, Varese, Italy

C Luini

Clinica Pediatrica, Università dell’Insubria, Varese, Italy

B Bettini

Centro Studi, Sclerosi Multipla, Ospedale di Gallarate, Italy

A Zibetti

Centro Studi, Sclerosi Multipla, Ospedale di Gallarate, Italy

L Nespoli

Clinica Pediatrica, Università dell’Insubria, Varese, Italy

G V.Melzi d'Eril

Dipartimento di Biochimica, Università dell’Insubria, Varese, Italy

Multiple sclerosis and celiac disease are both considered immune-mediated diseases. Recently, improved serological screening methods provided a higher prevalence of celiac disease (CD) in the general population worldwide and also demonstrated gastrointestinal symptoms may be lacking. The aim of this study was to determine the prevalence of (CD) in an unselected group of 95 adults with multiple sclerosis using transglutaminase antibodies. No patients showed pathological values. Different immune and genetic basis between the two diseases may represent crucial insights to explain our results.

Key Words: multiple sclerosis • celiac disease • transglutaminase • interferon • gastrointestinal disease

Multiple Sclerosis, Vol. 10, No. 6, 711-712 (2004)
DOI: 10.1191/1352458504ms1113sr
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This article has been cited by other articles:


Home page
 Mult SclerHome page
A Nicoletti, F Patti, S Lo Fermo, A Sciacca, P Laisa, A Liberto, S Lanzafame, D Contraffatto, C D'Agate, A Russo, et al.
Frequency of celiac disease is not increased among multiple sclerosis patients
Multiple Sclerosis, June 1, 2008; 14(5): 698 - 700.
[Abstract] [PDF]


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