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Hereditary Melkersson-Rosenthal syndrome and multiple sclerosis

International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba, cabrera.gomez{at}infomed.sld.cu, cineuro{at}neuro.sld.cu

N Echazabal-Santana

International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

Y Real-González

International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

K Romero García

International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

Manuel Junior Sobrinho

International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

M A Gil Ocaña

International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

N González-Valdes

Cuban Society of Multiple Sclerosis, Havana, Cuba

M L Valdes-Montes de Oca

Cuban Society of Multiple Sclerosis, Havana, Cuba

M Cristofol-Corominas

International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

J González de la Nuez

Cuban Society of Multiple Sclerosis, Havana, Cuba

J García Lahera

Cuban Society of Multiple Sclerosis, Havana, Cuba

C Ugarte uárez

Cuban Society of Multiple Sclerosis, Havana, Cuba

The revision of MEDLINE from 1966 to 2003 did not report any association between multiple sclerosis (MS) and Melkersson—Rosenthal syndrome (MRS). This is a case report of a 51-year-old woman, with history of four recurrent Bell’s palsies. In 1999 she developed a right facial paralysis due to a supranuclear pyramidal lesion with right monoparesis. The family history showed five relatives with recurrent Bell’s paralysis and plicata tongue. Physical examination: right Bell’s paralysis, left supranuclear facial paralysis, furrowed tongue, right hemiparesis with pallor of the optic disks. Brain magnetic resonance imaging (MRI) demonstrated the typical lesions of MS and CSF oligoclonal bands. This is the first observation of a patient with hereditary MRS and MS. The link between both diseases is discussed.

Key Words: Melkersson-Rosenthal syndrome • multiple sclerosis • multiple sclerosis relapsing-remitting

Multiple Sclerosis, Vol. 11, No. 3, 364-366 (2005)
DOI: 10.1191/1352458505ms1164cr


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