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Multiple Sclerosis
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Autoimmune hepatitis and multiple sclerosis: a coincidental association?

J de Seze

Department of Neurology, University of Lille, France, j-deseze{at}chru-lille.fr

V Canva-Delcambre

Department of Hepatology, University of Lille, France

I Fajardy

Department of Biochemistry, University of Lille, France

S Delalande

Department of Neurology, University of Lille, France

T Stojkovic

Department of Neurology, University of Lille, France

E Godet

Department of Neurology, Hospital of Metz, France

P Vermersch

Department of Neurology, University of Lille, France

In the present study we report, as part of a large multiple sclerosis (MS) cohort (1800 patients), three cases of untreated patients who developed autoimmune hepatitis (AIH). The prevalence of AIH in the general population is about 0.0169% and seems to be higher in our MS cohort (0.17%). We suggest that a liver biopsy should systematically be performed in untreated MS patients with a sustained increase of liver enzyme.

Key Words: autoimmune hepatitis • biopsy • HLA • interferor enzyme • multiple sclerosis

Multiple Sclerosis, Vol. 11, No. 6, 691-693 (2005)
DOI: 10.1191/1352458505ms1239oa
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This article has been cited by other articles:


Home page
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C. Hotermans, S. Belachew, G. Moonen, and J. Delwaide
Severe liver dysfunction in a patient with multiple sclerosis: the guilty party is not always the disease-modifying therapy
Multiple Sclerosis, November 1, 2009; 15(11): 1378 - 1379.
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