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Intrathecal baclofen for treatment of spasticity of multiple sclerosis patients

Service de Médecine Physique et Réadaptation, Hôpital R. Poincaré, 104 Bd R. Poincaré, 92380 Garches, djamel.bensmail{at}rpc.aphp.fr

A Peskine

Service de Médecine Physique et Réadaptation, Hôpital R. Poincaré, 104 Bd R. Poincaré, 92380 Garches

N Roche

Service de Médecine Physique et Réadaptation, Hôpital R. Poincaré, 104 Bd R. Poincaré, 92380 Garches

L Mailhan

Service de Médecine Physique et Réadaptation, Hôpital L. Bellan, 19-21 rue Vercingétorix, 75014 Paris

J B Thiébaut

Service de Neurochirurgie, Fondation Rothschild, 25-29 rue Manin, 75019 Paris, France

B Bussel

Service de Médecine Physique et Réadaptation, Hôpital R. Poincaré, 104 Bd R. Poincaré, 92380 Garches

We conducted a retrospective study of the case files of 64 multiple sclerosis (MS) patients presenting severe spasticity, who had received intrathecal (IT) baclofen test injections between 1992 and 2004 in a rehabilitation unit. In almost all cases of our series, IT baclofen was proposed to patients who were no longer able to walk. IT baclofen is a safe and effective treatment to reduce spasticity in MS patients. Despite an advanced stage of the disease at the time of pump placement, the complication rate was low and the efficacy of this treatment was maintained over time.

Key Words: intrathecal baclofen • multiple sclerosis • spasms • spasticity

Multiple Sclerosis, Vol. 12, No. 1, 101-103 (2006)
DOI: 10.1191/1352458506ms1232sr


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