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Multiple Sclerosis
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Recurrent optic neuromyelitis with endocrinopathies: a new syndrome or just a coincidence?

D Petravic

University Department of Neurology, Zagreb School of Medicine and University Hospital Center, Kispaticeva 12, HR- 10000 Zagreb, Croatia

M Habek

University Department of Neurology, Zagreb School of Medicine and University Hospital Center, Kispaticeva 12, HR- 10000 Zagreb, Croatia, mhabek{at}mef.hr

S Supe

University Department of Neurology, Zagreb School of Medicine and University Hospital Center, Kispaticeva 12, HR- 10000 Zagreb, Croatia

V V Brinar

University Department of Neurology, Zagreb School of Medicine and University Hospital Center, Kispaticeva 12, HR- 10000 Zagreb, Croatia

The spectrum of optic neuromyelitis (ONM) ranges from monophasic or recurrent idiopathic forms of the disease, to ONM associated with autoimmune disorders. A distinct form of the disease, called recurrent ONM with endocrinopathies, characterized by spinal cord involvement (cavitations with syringomyeloid sensory disturbance), rapid evolution to blindness and paraplegia, characteristic cerebrospinal fluid (CSF) findings, and association with hypothalamus - pituitary dysfunction, has recently been described. The first case of ONM with endocrinopathies in a female Caucasian from Europe is presented, supporting the existence of this syndrome as a separate entity.

Key Words: endocrinopathies • optic neuritis • optic neuromyelitis • transverse myelitis

Multiple Sclerosis, Vol. 12, No. 5, 670-673 (2006)
DOI: 10.1177/1352458506070756
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