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This version was published on March 1, 2007
Multiple Sclerosis, Vol. 13, No. 2, 224-231 (2007)
DOI: 10.1177/1352458506070663

Locomotor training using body weight support on a treadmill improves mobility in persons with multiple sclerosis: a pilot study

Barbara Giesser

Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA, bgiesser{at}mednet.ucla.edu

Janell Beres-Jones

Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA

Amy Budovitch

Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA

Elise Herlihy

Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA

Susan Harkema

Department of Neurological Surgery, University of Louisville, Frazier Rehab Institute, Louisville, KY, USA

Rationale The purpose of this protocol was to investigate the potential benefits and tolerability of locomotor training using body weight support on a treadmill (LTBWST) in persons with multiple sclerosis (MS).

Methods Four persons with primarily spinal cord MS and severely impaired ambulation (Expanded Disability Status Scale score 7.0-7.5) were enrolled in LTBWST. Subjects completed an average of 40 training sessions over several months.

Results Subjects showed improvement in muscle strength, spasticity, endurance, balance, walking speed, and quality of life at the end of the training sessions, and could tolerate training without fatigue or other adverse effects.

Conclusions LTBWST is well tolerated by persons with MS and may produce improvements in parameters related to functional mobility.

Key Words: ambulation • disability • multiple sclerosis • quality of life • rehabilitation • spasticity


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