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Multiple Sclerosis
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Multiple sclerosis in Pakistan

M. Wasay

The Aga Khan University, Karachi, Pakistan, mohammad.wasay{at}aku.edu

S. Ali

Jinnah Post Graduate Medical Center, Karachi, Pakistan

I.A. Khatri

Liaquat National Hospital, Karachi, Pakistan

A. Hassan

Shifa International Hospital, Islamabad, Pakistan

M. Asif

Baqai Medical University, Karachi, Pakistan

N. Zakiullah

The Aga Khan University, Karachi, Pakistan

A. Ahmed

Shifa International Hospital, Islamabad, Pakistan

A. Malik

Jinnah Post Graduate Medical Center, Karachi, Pakistan

B. Khealani

The Aga Khan University, Karachi, Pakistan

A. Haq

Al-Aman Hospital, Peshawar, Pakistan

S. Fredrikson

Karolinska Institute, Stockholm, Sweden

We describe retrospective data from the largest series of patients (n=142) with multiple sclerosis (MS) from Pakistan. Mean age at onset was 27 years, with a female to male ratio of 1.45:1. The disease onset was polysymptomatic in 75% patients. Motor weakness was the most common onset symptom (70%), followed by sensory symptoms (45%). Optico-spinal type of MS was seen in only 3% of patients The courzse was relapsing-remitting (RR) in 81%, primary progressive (PP) in 21%, and secondary progressive (SP) in 4% of patients. Almost three-fourths of the patients were moderately (45%) or severely (31%) disabled at the time of evaluation. Two-thirds of patients with severe disability had a mean disease duration of only 5.2 years. In conclusion, MS is not uncommon in Pakistan, and many patients were found to have severe disability despite short disease duration. Multiple Sclerosis 2007; 13: 668-669. http://msj.sagepub.com

Key Words: analysis • multiple sclerosis • Pakistan • review

This version was published on June 1, 2007

Multiple Sclerosis, Vol. 13, No. 5, 668-669 (2007)
DOI: 10.1177/1352458506072339
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