SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Multiple Sclerosis
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
1352458507076411v1
13/7/880    most recent
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (8)
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Zhang, Y.
Right arrow Articles by Mitchell, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhang, Y.
Right arrow Articles by Mitchell, J.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Deep grey matter `black T2` on 3 tesla magnetic resonance imaging correlates with disability in multiple sclerosis

Y. Zhang

Department of Radiology, University of Calgary, Calgary T2N 2T9, Canada, Hotchkiss Brain Institute, University of Calgary, Calgary T2N 2T9, Canada

RK Zabad

Hotchkiss Brain Institute, University of Calgary, Calgary T2N 2T9, Canada, Department of Clinical Neurosciences, University of Calgary, Calgary T2N 2T9, Canada th

X. Wei

Department of Radiology, University of Calgary, Calgary T2N 2T9, Canada

LM Metz

Hotchkiss Brain Institute, University of Calgary, Calgary T2N 2T9, Canada, Department of Clinical Neurosciences, University of Calgary, Calgary T2N 2T9, Canada th

MD Hill

Hotchkiss Brain Institute, University of Calgary, Calgary T2N 2T9, Canada, Department of Clinical Neurosciences, University of Calgary, Calgary T2N 2T9, Canada th

JR Mitchell

Department of Radiology, University of Calgary, Calgary T2N 2T9, Canada, Hotchkiss Brain Institute, University of Calgary, Calgary T2N 2T9, Canada, Department of Clinical Neurosciences, University of Calgary, Calgary T2N 2T9, Canada, rmitch{at}ucalgary.ca

T2 hypointensity (black T2, BT2) in the deep grey matter of multiple sclerosis (MS) patients correlate weakly with disability at 1.5 T. BT2 is likely to be caused by abnormal iron deposition. We compared the correlation between disability and deep grey matter BT2 measured on 3 T MRI and on 1.5 T MRI in 17 MS patients. We observed a significant correlation between expanded disability status scale and signal intensity on 3 T MRI in the globus pallidus and the caudate nucleus (r = —0.5, P < 0.05). BT2 at 3 T may be a useful MRI measure associated with disability in MS and warrants further study. Multiple Sclerosis 2007; 13: 880—883. http://msj.sagepub.com

Key Words: black T2 • high field MRI • multiple sclerosis • disability • deep grey matter • iron deposition

This version was published on August 1, 2007

Multiple Sclerosis, Vol. 13, No. 7, 880-883 (2007)
DOI: 10.1177/1352458507076411
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Mult SclerHome page
A. Ceccarelli, M. A Rocca, M. Neema, V. Martinelli, A. Arora, S. Tauhid, A. Ghezzi, G. Comi, R. Bakshi, and M. Filippi
Deep gray matter T2 hypointensity is present in patients with clinically isolated syndromes suggestive of multiple sclerosis
Multiple Sclerosis, January 1, 2010; 16(1): 39 - 44.
[Abstract] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
B Healy, P Valsasina, M Filippi, and R Bakshi
Sample size requirements for treatment effects using gray matter, white matter and whole brain volume in relapsing-remitting multiple sclerosis
J. Neurol. Neurosurg. Psychiatry, November 1, 2009; 80(11): 1218 - 1224.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
U. Walter, S. Wagner, S. Horowski, R. Benecke, and U. K. Zettl
Transcranial brain sonography findings predict disease progression in multiple sclerosis
Neurology, September 29, 2009; 73(13): 1010 - 1017.
[Abstract] [Full Text] [PDF]

Home page
 Mult SclerHome page
A Ceccarelli, M Filippi, M Neema, A Arora, P Valsasina, M. Rocca, B. Healy, and R Bakshi
T2 hypointensity in the deep gray matter of patients with benign multiple sclerosis
Multiple Sclerosis, June 1, 2009; 15(6): 678 - 686.
[Abstract] [PDF]

Home page
 Mult SclerHome page
B Holst, S Siemonsen, J Finsterbusch, M Bester, S Schippling, R Martin, and J Fiehler
T2' imaging indicates decreased tissue metabolism in frontal white matter of MS patients
Multiple Sclerosis, June 1, 2009; 15(6): 701 - 707.
[Abstract] [PDF]


Advertisement