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First published on January 21, 2008, doi:10.1177/1352458507084596
This version was published on January 31, 2008


Article

Sexual dysfunction in newly diagnosed multiple sclerosis women

Vassilios Tzortzis1*, Konstantinos Skriapas1, George Hadjigeorgiou1, Iraklis Mitsogiannis2, Konstantinos Aggelakis1, Stavros Gravas1, Vassilios Poulakis2, and Michael D. Melekos1

1 Department of Urology, University of Thessaly School of Medicine, Larissa, Greece
2 Department of Neurology, University of Thessaly School of Medicine, Larissa, Greece

* To whom correspondence should be addressed.


   Abstract

Objectives:

The aim of the study was to evaluate female sexuality in a selective population of newly diagnosed multiple sclerosis (MS) women. ?

Materials and methods:

In this clinic-based study, 63 newly diagnosed consecutive women affected by definite MS were admitted. Disability and depression were evaluated with the expanded disability status scale (EDSS) and Beck depression inventory, respectively. Sexual function was evaluated with the female sexual function index (FSFI). A group of 61 healthy female volunteers with the same baseline characteristics were used as controls. Postmenopausal women and patients with other major concomitant neurological, endocrinological, vascular, gynecological, psychiatric disorders, use of medicines that can cause female sexual dysfunction (FSD) and disease-modifying drugs were excluded from the study.

Results

All the evaluated patients were ambulant with no major neurological impairment (mean EDSS score 2.5, range 0–3.5). None of the patients were considered clinically depressed, but some of them were sad or worried. According to the sexual history and FSFI scores, sexual dysfunction was diagnosed in 22 (34.9%) out of the 63 patients and in 13 (21.31%) out of the 61 healthy females (P _ 0.05).

Conclusions

In the newly diagnosed MS patients, FSD represent an important issue even though disability and other concomitant disorders affecting sexual function were excluded.

Key Words: sexual dysfunction; multiple sclerosis; FSFI


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