This Article Full Text (PDF) All Versions of this Article: 1352458507080464v1 14/1/129    most recent References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (9) Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Motl, R.W. Articles by Gosney, J.L. Search for Related Content PubMed PubMed Citation Articles by Motl, R.W. Articles by Gosney, J.L. Pubmed/NCBI databases Medline Plus Health Information Exercise for Children Exercise and Physical Fitness Multiple Sclerosis Social Bookmarking                         What's this?

Effect of exercise training on quality of life in multiple sclerosis: a meta-analysis

Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, IL 61801, USA, robmotl{at}uiuc.edu

J.L. Gosney

Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, IL 61801, USA

Using meta-analytic procedures, this study examined the overall effect of exercise training interventions on quality of life (QOL) among individuals with multiple sclerosis (MS). We searched MEDLINE, PSYCHINFO and CURRENT CONTENTS PLUS for the period of 1960 to November 2006 using the key words exercise, physical activity and physical fitness in conjunction with QOL and MS. We further conducted a manual search of bibliographies of the retrieved papers as well as literature reviews and contacted study authors about additional studies. Twenty-five journal articles were located and reviewed, and only 13 provided enough data to compute effect sizes expressed as Cohen's d. One hundred and nine effect sizes were retrieved from the 13 studies with 484 MS participants and yielded a weighted mean effect size of g = 0.23 (95% CI = 0.15, 0.31). There were larger effects associated with MS-specific measures of QOL and fatigue as an index of QOL. The nature of the exercise stimulus further influenced the magnitude of the mean effect size. The cumulative evidence supports that exercise training is associated with a small improvement in QOL among individuals with MS. Multiple Sclerosis 2008; 14: 129—135. http://msj.sagepub.com

Key Words: exercise training • fatigue • multiple sclerosis • physical activity • quality of life

This version was published on January 1, 2008

Multiple Sclerosis, Vol. 14, No. 1, 129-135 (2008)
DOI: 10.1177/1352458507080464


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				E. McAuley, S. M. White, L. Q. Rogers, R. W. Motl, and K. S. Courneya Physical Activity and Fatigue in Breast Cancer and Multiple Sclerosis: Psychosocial Mechanisms Psychosom Med, January 1, 2010; 72(1): 88 - 96. [Abstract] [Full Text] [PDF]

				N. Mayo and M Asano Not another meta-analysis! Multiple Sclerosis, April 1, 2009; 15(4): 409 - 411. [PDF]