SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Multiple Sclerosis
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
1352458507082053v1
1352458507082053v2
14/2/262    most recent
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Aguirregomozcorta, M.
Right arrow Articles by Genís, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Aguirregomozcorta, M.
Right arrow Articles by Genís, D.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Paroxysmal dystonia and pathological laughter as a first manifestation of multiple sclerosis

M. Aguirregomozcorta

Neuroimmunology and Multiple Sclerosis Unit, Department of Neurology, Hospital Dr Josep Trueta, Girona, Spain, maria6478{at}yahoo.es

LI Ramió-Torrentà

Neuroimmunology and Multiple Sclerosis Unit, Department of Neurology, Hospital Dr Josep Trueta, Girona, Spain

J. Gich

Neuroimmunology and Multiple Sclerosis Unit, Department of Neurology, Hospital Dr Josep Trueta, Girona, Spain

A. Quiles

MRI Unit - IDI, Department of Radiology, Hospital Dr Josep Trueta, Girona, Spain

D. Genís

Neuroimmunology and Multiple Sclerosis Unit, Department of Neurology, Hospital Dr Josep Trueta, Girona, Spain

Paroxysmal dystonia is an uncommon but well-established feature of multiple sclerosis (MS). Attacks can occur in established MS and may even occasionally be the initial symptom of this disorder. Pathological laughter is usually seen as a pseudobulbar palsy in some diffuse neurological diseases, but cases have been described, mostly in ischaemic attacks or tumours, where it is presented as bursts of laughter of variable duration. The pathogenesis of neither of the two phenomena has been fully established but both have been reported as being positive phenomena resulting from ectopic activation with ephaptic spread. We describe the first reported case of a paroxysmal hemidystonia together with bursts of pathological laughter as the first manifestation of MS. Multiple Sclerosis 2008; 14: 262—265. http://msj.sagepub.com

Key Words: demyelination • ephaptic • multiple sclerosis • paroxysmal dystonia • pathological laughter • tonic seizures • tonic spasms

This version was published on March 1, 2008

Multiple Sclerosis, Vol. 14, No. 2, 262-265 (2008)
DOI: 10.1177/1352458507082053
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?




Advertisement