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Multiple Sclerosis
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What's this?

short-report

Frequency of celiac disease is not increased among multiple sclerosis patients

A Nicoletti

Dipartimento di Neuroscienze, Università di Catania, Catania, Italy

F Patti

Dipartimento di Neuroscienze, Università di Catania, Catania, Italy

S Lo Fermo

Dipartimento di Neuroscienze, Università di Catania, Catania, Italy

A Sciacca

Dipartimento di Scienze Microbiologiche e Ginecologiche, Università di Catania, Catania, Italy

P Laisa

Dipartimento di Neuroscienze, Università di Catania, Catania, Italy

A Liberto

Dipartimento di Neuroscienze, Università di Catania, Catania, Italy

S Lanzafame

Dipartimento di Neuroscienze, Università di Catania, Catania, Italy

D Contraffatto

Dipartimento di Neuroscienze, Università di Catania, Catania, Italy

C D’Agate

Unità Operativa di Gastroenterologia ed Endoscopia digestiva, Università di Catania, Catania, Italy

A Russo

Unità Operativa di Gastroenterologia ed Endoscopia digestiva, Università di Catania, Catania, Italy

M Zappia

Dipartimento di Neuroscienze, Università di Catania, Catania, Italy, m.zappia{at}isn.cnr.it

We evaluated the presence of IgA and IgG celiac disease–related antibodies in a sample of 217 patients with multiple sclerosis (MS) and in a sample of 200 controls not affected by neurological disorders. None of the 217 patients with MS presented IgG and IgA anti-gliadin, anti-endomysial antibodies, anti-tissue transglutaminase and anti-reticulin, whereas only one of the selected controls presented specific antibodies; this subject resulted to be effectively affected by celiac disease. Our data did not show an increased frequency of celiac disease among patients with MS.

Key Words: multiple sclerosis • celiac disease

Multiple Sclerosis, Vol. 14, No. 5, 698-700 (2008)
DOI: 10.1177/1352458507087268
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