This Article Full Text (PDF) All Versions of this Article: 1352458508098561v1 15/3/285    most recent References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Pichiecchio, A Articles by Bastianello, S Search for Related Content PubMed PubMed Citation Articles by Pichiecchio, A Articles by Bastianello, S Social Bookmarking                         What's this?

What insights have new imaging techniques given into aggressive forms of MS – different forms of MS or different from MS?

Neuroradiology Unit, Neurological Institute IRCCS "Fondazione C. Mondino," Pavia, Italy anna.pichiecchio{at}mondino.it

E Tavazzi

Multiple Sclerosis Centre, Neurological Institute IRCCS "Fondazione C. Mondino," Pavia, Italy

G Maccabelli

Neuroradiology Unit, Neurological Institute IRCCS "Fondazione C. Mondino," Pavia, Italy

CM Precupanu

Department of Hematology and Oncology, Hospital Hotel-Dieu, Paris, France

A Romani

Multiple Sclerosis Centre, Neurological Institute IRCCS "Fondazione C. Mondino," Pavia, Italy

L Roccatagliata

Department of Neuroscience, Ophthalmology and Genetics, University of Genoa, Genoa, Italy

G Luccichenti

Neuroimaging Laboratory, IRCCS "Fondazione Santa Lucia," Rome, Italy

R Bergamaschi

Multiple Sclerosis Centre, Neurological Institute IRCCS "Fondazione C. Mondino," Pavia, Italy

S Bastianello

Neuroradiology Unit, Neurological Institute IRCCS "Fondazione C. Mondino," Pavia, Italy

"Aggressive" multiple sclerosis (MS) is still a challenging diagnosis, in spite of the relevant progresses concerning the comprehension of the disease mechanisms, especially through pathology studies and the advent of conventional magnetic resonance imaging (MRI). Some reviews have been already published on their clinical and therapeutical aspects, but no systematic review is available in literature about the neuroradiological features, using both conventional and advanced techniques. In particular, advanced MRI techniques, namely diffusion-weighted and tensor imaging, magnetization transfer imaging, and proton magnetic resonance spectroscopy, are giving new insights to find specific and appropriate radiological parameters that can help in targeting the diagnosis. We report a review of literature on the neuroradiological findings of aggressive forms of MS, focusing specifically on the role of advanced MRI techniques in the diagnostic phase and during follow-up.

Key Words: aggressive MS • DWI • magnetization transfer • MR spectroscopy • pseudotumoral MS

This version was published on March 1, 2009

Multiple Sclerosis, Vol. 15, No. 3, 285-293 (2009)
DOI: 10.1177/1352458508098561


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?