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Multiple Sclerosis
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What's this?

case-report

Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis

J Liang

Department of Immunology and Rheumatology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, P. R. China

H Zhang

Department of Immunology and Rheumatology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, P. R. China

B Hua

Department of Immunology and Rheumatology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, P. R. China

H Wang

Department of Immunology and Rheumatology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, P. R. China

J Wang

Institute of Hematology, CAMS & PUMC, Tianjing 300020, P. R. China

Z Han

Institute of Hematology, CAMS & PUMC, Tianjing 300020, P. R. China

L Sun

Department of Immunology and Rheumatology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, P. R. China lingyunsun2001{at}yahoo.com.cn

Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system. Umbilical cord derived mesenchymal stem cells are immunosuppressive. We transplanted mesenchymal stem cells in a patient with refractory progressive MS, and the disease course was stabilized after the transplantation. We postulate that mesenchymal stem cells have a potent immunosuppressive effect in vivo.

Key Words: multiple sclerosis • T2 lesions

Multiple Sclerosis, Vol. 15, No. 5, 644-646 (2009)
DOI: 10.1177/1352458509104590
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