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Long term use of Desmopressin for urinary symptoms in multiple sderosis

Department of Neurology, Mayday Hospital, Mayday Road, Thornton Heath, Surrey, CRO 7YE

R Addison

Lan caster Suite, Continence Department, Mayday Hospital, Mayday Road, Thornton Heath, Surrey, CRO 7YE

F Schon

Department of Neurology, Mayday Hospital, Mayday Road, Thornton Heath, Surrey, CRO 7YE

The benefit of desmopressin (DDAVP) in the treatment of the urinary symptoms of multiple sclerosis has until now only been shown in short crossover studies of up to 6 weeks. We report 19 patient who have used the drug for an average of 2 years and 4 months, 18 of whom confirmed continued dramatic benefit without any obvious change in dosage used or efficacy and with few side effects. Ten of the 19 patienit had also used DDAVP during daytime for special occasions with notable success. This is the first study to suggest that DDAVP is safe and effective in long term use in MS.

Key Words: multiple sclerosis • nocturia • desmopressin

Multiple Sclerosis, Vol. 5, No. 6, 416-417 (1999)
DOI: 10.1177/135245859900500i608


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