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Multiple Sclerosis
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Histocompatibility antigen (HLA) associations with multiple sclerosis in Iran

H Kalanie

Department of Neurology Shohada Hospital, Tajrish, Tehran, Iran

M Kamgooyan

Iranian Blood Transfusion Organization, Nejatollahie Street, Tehran, Iran

H Sadeghian

Department of Neurology Shohada Hospital, Tajrish, Tehran, Iran

A R Kalanie

University of Otago Medical School, Christchurch, New Zealand

Human leukocyte antigen (HLA) types were obtained from 79 Iranian patients with multiple sclerosis and compared with 100 controls. The prevalence of HLA-A24 (30.3% versus 18.0%), HLA-DR2 (43.0% versus 28.0%) and HLA-DR15 (36.7% versus 23.0%) were significantly increased in multiple sclerosis patients compared with controls. However age at onset, and disease status (relapsing-remitting or primary progressive) did not show an association with any particular HLA type.

Key Words: HLA • multiple sclerosis • Iran

Multiple Sclerosis, Vol. 6, No. 5, 317-319 (2000)
DOI: 10.1177/135245850000600504
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