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Multiple Sclerosis, Vol. 7, No. 1, 67-70 (2001)
DOI: 10.1177/135245850100700111

Episodic hyperlibidinism in multiple sclerosis

Francisco de Assis Aquino Gondim

Department of Neurology, Saint Louis University School of Medicine, St Louis, Missouri, USA

Florian P Thomas

St. Louis Veterans Administration Hospital, Saint Louis University School of Medicine, St Louis, Missouri, USA, Department of Neurology, Saint Louis University School of Medicine, St Louis, Missouri, USA, Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St Louis, Missouri, USA, Institute for Molecular Virology, Saint Louis University School of Medicine, St Louis, Missouri, USA

Background: Changes in sexual function are commonly associated with MS and occur in many forms. Hypersexual thought or behavior are rare, but can present on the background of persistent cognitive impairment or psychiatric conditions such as mania, whereas isolated hypersexuality is still rarer. Case Report: We describe the clinical neuropsychological electrodiagnostic neuroimaging and endocrine findings in a MS patient with episodes of greatly increased libido. Imaging and neuropsychological studies indicated frontal lobe dysfunction; hormone studies showed no significant changes. Conclusion: Episodic hypersexuality can be a recurrent transient manifestation of MS.

Key Words: MS • demyelination • sexual behavior • sexual dysfunction • libido • SPECT • MRI


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