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Multiple Sclerosis
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Horizontal monocular saccadic failure: an unusual clinically isolated syndrome progressing to multiple sclerosis

Elliot M Frohman

Department of Neurology and Ophthalmology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75235, USA, elliot.frohman{at}utsouthwestern.edu

Teresa C Frohman

Department of 1Neurology

This paper describes an unusual clinically isolated syndrome of inflammatory demyelination that was characterized by a right VI nerve palsy and right internuclear ophthalmoparesis (INO), along with an unusual form of dissociated nystagmus. Magnetic resonance imaging (MRI) revealed an isolated lesion within the right dorsomediolateral pontine tegmentum. Four years later, the subject developed a partial sensory transverse myelitis, confirming clinically definite multiple sclerosis (MS). This paper extends the range of isolated syndromes associated with MS.

Key Words: abducens palsy • clinically isolated syndrome • internuclear ophthalmoparesis

Multiple Sclerosis, Vol. 9, No. 1, 55-58 (2003)
DOI: 10.1191/1352458503ms864oa
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This article has been cited by other articles:


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[Abstract] [Full Text] [PDF]


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