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Multiple sclerosis characteristics in A frican A merican patients in the New York State Multiple Sclerosis C onsortiumWilliam C. Baird Multiple Sclerosis Research Center, The Jacobs Neurological Institute, Buffalo, NY 14203, USA, BWeinstock-Guttman{at}KaleidaHealth.org
William C. Baird Multiple Sclerosis Research Center, The Jacobs Neurological Institute, Buffalo, NY 14203, USA, Deceased
William C. Baird Multiple Sclerosis Research Center, The Jacobs Neurological Institute, Buffalo, NY 14203, USA
Center for Research Methodology and Biometrics, AMC Cancer Research Center, Lakewood, CO 80214, USA
William C. Baird Multiple Sclerosis Research Center, The Jacobs Neurological Institute, Buffalo, NY 14203, USA
Department of Neurology and Neuroscience, Cornell Medical Center, New York, NY 10021, USA
Multiple Sclerosis Care Center, North Shore University Hospital at East Meadow, East Meadow, NY 11554, USA
Department of Neurology, State University of New York at Stony Brook University Hospital, Stony Brook, NY 11794, USA
Kingston Neurological Associates, Kingston, NY 12401, USA
Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA
Division of Neurology, Winthrop-University Hospital, Mineola, NY 11501, USA
The Hospital for Joint Diseases/Orthopedic Institute, MS Care Center, New York, NY 10003, USA
Neurological Associates of Albany, Albany, NY 12208, USA
Department of Neurology, Albany Medical College, Albany, NY 12208, USA
Glens Falls Neurology, Glens Falls, NY 12801, USA
Catskill Neuroscience and Radiology Associates, Oneonta, NY 13820, USA
Department of Neurology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
Division of Neurology, Maimonides Medical Center, Brooklyn, NY 11219, USA
Staten Island University Hospital, Staten Island, NY 10306, USA
New York Hospital Medical Center of Queens, Flushing, NY 11355, USA
William C. Baird Multiple Sclerosis Research Center, The Jacobs Neurological Institute, Buffalo, NY 14203, USA
Uniform Data System for Medical Rehabilitation, State University of New York at Buffalo
William C. Baird Multiple Sclerosis Research Center, The Jacobs Neurological Institute, Buffalo, NY 14203, USA
Department of Neurology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
Department of Neurology, State University of New York at Stony Brook University Hospital, Stony Brook, NY 11794, USA
William C. Baird Multiple Sclerosis Research Center, The Jacobs Neurological Institute, Buffalo, NY 14203, USA
Division of Neurology, Winthrop-University Hospital, Mineola, NY 11501, USA
Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA
Department of Neurology, State University of New York at Stony Brook University Hospital, Stony Brook, NY 11794, USA The New York State Multiple Sclerosis Consortium The objective of this study was to determine the clinical characteristics of multiple sclerosis (MS) in A frican A merican (A A) patients in the New York State Multiple Sclerosis C onsortium (NYSMSC) patient registry. The NYSMSC is a group of 18 MS centers throughout New York State organized to prospectively assess clinical characteristics of MS patients. AA s comprise 6% (329) of the total NYSMSC registrants (5602). Demographics, disease course, therapy, and socioeconomic status were compared in A A registrants versus nonA frican A mericans (NA A). There was an increased female preponderance and a significantly younger age at diagnosis in the AA group. A A patients were more likely to have greater disability with increased disease duration. No differences were seen in types of MS and use of disease modifying therapies. O ur findings suggest a racial influence in MS. Further genetic studies that consider race differences are warranted to elucidate mechanisms of disease susceptibility.
Key Words: African A mericans • autoimmune disease • demyelinating disease • epidemiology • genetics • multiple sclerosis • neurodegenerative disease
Multiple Sclerosis, Vol. 9, No. 3,
293-298 (2003) This article has been cited by other articles:
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