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A cute verbal dyspraxia, a rare presentation in multiple sclerosis: a case report with MRI localization

Department of Neurology, Louisiana State University School of Medicine - Shreveport, 1501 Kings Highway, Shreveport, LA 71130, USA

Michael F Glabus

Department of Psychiatry, Louisiana State University School of Medicine - Shreveport, 1501 Kings Highway, Shreveport, LA 71130, USA

Roger E Kelley

Department of Neurology, Louisiana State University School of Medicine - Shreveport, 1501 Kings Highway, Shreveport, LA 71130, USA

Alireza Minagar

Department of Neurology, Louisiana State University School of Medicine - Shreveport, 1501 Kings Highway, Shreveport, LA 71130, USA, aminag{at}lsuhsc.edu

C ortical speech disorders rarely occur in multiple sclerosis (MS). We report a patient with relapsing-remitting MS, who presented with acute verbal dyspraxia. Magnetic resonance imaging (MRI) demonstrated an acute T2/Flair hyperintense, primarily white matter lesion underlying the middle third of the inferior frontal gyrus. The verbal dyspraxia cleared beginning 48 hours after the initiation of iv dexamethasone. Follow-up MRI demonstrated qualitative and quantitative diminution of the hyperintensity. This is the first report of a clinically definite MS patient with acute verbal dyspraxia. Moreover, there was a suggestive localization of verbal praxis to Brodmann areas 44/45.

Key Words: MRI localization • multiple sclerosis • verbal dyspraxia

Multiple Sclerosis, Vol. 9, No. 6, 630-632 (2003)
DOI: 10.1191/1352458503ms959cr


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