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Multiple Sclerosis
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Leopold Ordenstein: on paralysis agitans and multiple sclerosis

H.C. Lehmann

Department of Neurology, Heinrich-Heine-University Duesseldorf, Germany, helmar.lehmann{at}uni-duesseldorf.de

H.-P. Hartung

Department of Neurology, Heinrich-Heine-University Duesseldorf, Germany

B.C. Kieseier

Department of Neurology, Heinrich-Heine-University Duesseldorf, Germany

In 1868 the German Leopold Ordenstein (1835—1902) published in Paris a doctoral thesis in French language under the patronage of Jean-Martin Charcot (1825—1893). For the first time, multiple sclerosis and Parkinson's disease were clearly recognized as different clinical entities, based on clinical and pathological data. Ordenstein's work represents today a fundamental and often credited, yet still widely unknown, contribution to the history of these two diseases. The present paper delivers a synopsis of this key document. In addition, the life and work of Leopold Ordenstein will be reviewed. Multiple Sclerosis 2007; 13: 1195—1199. http://msj.sagepub.com

Key Words: biography • Charcot • history of medicine • multiple sclerosis • Parkinson disease

References

  • Bonduelle M., Gelfand T., Goetz C. Charcot, un grand médecin dans son siècle. Michalon, 1996.
  • Baas JH Leopold Ordenstein. Worms: Gebr. Hoffmann, 1904.
  • Ordenstein L. Über den Parotidenspeichel des Menschen. Giessen, 1859.
  • Ordenstein L. Sur la paralysie agitante et la sclérose en plaques généralisée. Delahaye, 1868.
  • Parkinson J. An essay on the shaking palsy. Sherwood, Neely and Jones, 1817.
  • Charcot JM, Vulpian A. De la paralysie agitante. Gaz hebdomadaire med chirurg 1861; 8: 765—67.
  • Tretiakoff C. Contributions a l'étude de l'anatomie pathologique du locus niger de Soemmering avec quelques déductions relatives a la pathogénie des troubles de tonus musculaire et de la maladie de Parkinson. Paris, 1919.
  • Foix C., Nicolesco J. Anatomie cerebrale: les noyaux gris centraux et la region mesencephalo-soux-optique. Masson, 1925.
  • Goetz CG, Bonduelle M. Charcot as therapeutic interventionist and treating neurologist. Neurology 1995; 45: 2102—2106.[Abstract/Free Full Text]
  • Sourkes TL " Rational hope" in the early treatment of Parkinson's disease. Can J Physiol Pharmacol 1999; 77.
  • Compston A. The story of multiple sclerosis. In Compston A, Ebers GC, Lassmann H, McDonald I, Mattews B, Wekerle H eds. McAlpine`s multiple sclerosis (third edition). Churchill Livingstone, 1998; 592.
  • Talley CL The emergence of multiple sclerosis as a nosological categories in France, 1838—1868. J Hist Neurosci 2003; 12: 250—65.
  • Goetz CG The prefaces of Charcot. Neurology 2003; 60: 1333—40.[Abstract/Free Full Text]

Multiple Sclerosis, Vol. 13, No. 9, 1195-1199 (2007)
DOI: 10.1177/1352458507076979


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This Article
Right arrow Abstract Freely available
Right arrow Free Full Text (Free PDF) Free
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Lehmann, H.C.
Right arrow Articles by Kieseier, B.C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lehmann, H.C.
Right arrow Articles by Kieseier, B.C.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
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