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Multiple Sclerosis
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1352458506070663v1
13/2/224    most recent
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Article

Locomotor training using body weight support on a treadmill improves mobility in persons with multiple sclerosis: a pilot study

Barbara Giesser1*, Janell Beres-Jones1, Amy Budovitch1, Elise Herlihy1, Susan Harkema2

1 Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA
2 Department of Neurological Surgery, University of Louisville, Frazier Rehab Institute, Louisville, KY, USA

* To whom correspondence should be addressed.


  Abstract

Rationale

The purpose of this protocol was to investigate the potential benefits and tolerability of locomotor training using body weight support on a treadmill (LTBWST) in persons with multiple sclerosis (MS).

Methods

Four persons with primarily spinal cord MS and severely impaired ambulation (Expanded Disability Status Scale score 7.0-7.5) were enrolled in LTBWST. Subjects completed an average of 40 training sessions over several months.

Results

Subjects showed improvement in muscle strength, spasticity, endurance, balance, walking speed, and quality of life at the end of the training sessions, and could tolerate training without fatigue or other adverse effects. Conclusions LTBWST is well tolerated by persons with MS and may produce improvements in parameters related to functional mobility.

Key Words: ambulation, disability, multiple sclerosis, quality of life, rehabilitation, spasticity

First published on January 29, 2007, doi:10.1177/1352458506070663

Multiple Sclerosis 2007;13:224.

A more recent version of this article appeared on March 1, 2007

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