Epidemiology of familial multiple sclerosis in Hungary

¹ Department of Neurology, Albert Szent-Gyögyi Medical and Pharmaceutical Centre, University of Szeged, Hungary
² Department of Neurology, University of Debrecen, Hungary
³ Department of Neurology, Szent Imre Hospital, Budapest, Hungary
⁴ Department of Neurology, Aviation Hospital, Kecskemét, Hungary
⁵ Department of Neurology, Jahn Ferenc Hospital of South-Pest, Budapest, Hungary
⁶ Department of Neurology, University of Pécs, Hungary

^* To whom correspondence should be addressed.

	Abstract

The prevalence of familial aggregation of multiple sclerosis (MS) is estimated between 5 and 10%. Studies emphasize the effect of genetic factors over the environment of the patients in the development of the disease. We investigated familial accumulation of MS in the cases of 1500 patients in five Hungarian MS centers. According to our data, the risk of familial MS in Hungary is lower than in other countries for which literature data are accessible. The literature does not contain any data for the prevalence of familial MS in Hungary and middle-eastern Europe.

Key Words: familial aggregation, first-degree relatives, genetic factors, multiple sclerosis, prevalence

First published on January 29, 2007, doi:10.1177/1352458506070767

Multiple Sclerosis 2007;13:260.

A more recent version of this article appeared on March 1, 2007


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