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Multiple Sclerosis
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Article

The relationship between neuropsychological measures and the Timed Instrumental Activities of Daily Living task in multiple sclerosis

Yael Goverover1, Helen M Genova1, Frank G Hillary2, John DeLuca1*

1 Kessler Medical Rehabilitation Research and Education Corporation, West Orange, NJ, USA
2 Department of Psychology, Pennsylvania State University, University Park, PA, USA

* To whom correspondence should be addressed.


  Abstract

Multiple sclerosis (MS) can result in cognitive deficits and a loss of functional independence.To date, little research has linked the observed cognitive and behavioral deficits in MS, especially those in the processing speed domain, to performance on tasks of everyday functioning. Thepresent study examined the relationship between neuropsychological test performance and performance on the Timed Instrumental Activities of Daily Living task (TIADL) in individuals with MS, and in healthy controls (HCs). The TIADL is a functional measure, which assesses both accuracy and speed in one's performance of everyday activities. The MS group performed significantly worse on the TIADL relative to the HC group. Additionally, TIADL scores of individuals with MS were significantly correlated with neuropsychological measures of processing speed. TIADL scores were not, however, correlated with neuropsychological measures of verbal episodic memory or working memory. These results indicate that the impairments in processing speed may contribute to impairments in activities of everyday living in persons with MS.

Key Words: cognitive functions, instrumental activities of daily living, multiple sclerosis, neuropsychological measures, processing speed, rehabilitation

First published on February 16, 2007, doi:10.1177/1352458506072984

Multiple Sclerosis 2007;13:636.

A more recent version of this article appeared on June 1, 2007

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