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Multiple Sclerosis
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Article

Impact of fatigue in multiple sclerosis: the Fatigue Impact Scale for Daily Use (D-FIS)

J Benito-León1*, P Martínez-Martín2, B Frades2, M L Martínez-Ginés3, C de Andrés3, J E Meca-Lallana4, A R Antigüedad5, B Huete-Antón5, E Rodríguez-García6, J Ruiz-Martínez7

1 Department of Neurology, Móstoles General Hospital, Madrid, Spain;
2 Unit of Neuroepidemiology, National Centre for Epidemiology, ISCIII, The Spanish Network HOHSR, Madrid, Spain;
3 Department of Neurology, Gregorio Marañón University Teaching Hospital, Madrid, Spain;
4 Department of Neurology, Virgen de la Arrixaca University Teaching Hospital, Murcia, Spain;
5 Department of Neurology, Basurto Hospital, Bilbao, Spain;
6 Department of Neurology, Severo Ochoa Hospital, Leganés, Madrid, Spain;
7 Department of Neurology, Mendaro Hospital, Guipúzcoa, Spain

* To whom correspondence should be addressed.


  Abstract

Objective

The Fatigue Impact Scale for Daily Use (D-FIS) is an eight-item instrument designed to measure subjective daily experience of fatigue. This study sought to determine the metric properties of the D-FIS in multiple sclerosis (MS) patients.

Methods

Sixty-eight patients with operationally-defined MS and fatigue (54.8% of the sample) underwent the D-FIS. Usual clinical measures for MS, the Montgomery-Asberg Depression Rating Scale (MADRS) and the Functional Assessment of Multiple Sclerosis (FAMS) were also applied. In addition, patients with fatigue completed the Fatigue Descriptive Scale, the Multidimensional Fatigue Inventory (MFI), a Visual Analogue Scale for Fatigue (VAS-F), and a Global Perception of Fatigue Scale (GPF).

Results

Full computable data, 95.6%; both floor and ceiling effect=1.54%; item-total correlation =0.62 (item 1) to 0.84 (item 6); Cronbach's alpha=0.91; item homogeneity=0.55; standard error of measurement=3.18; convergent validity with other fatigue measures= - 0.57 (VAS-F); 0.52 (GPF); and 0.46 (MFI-general fatigue). Test-retest reliability (ICC)=0.81. There was a strong association between health-related quality of life (HRQoL) (FAMS) and D-FIS (rS=0.70).

Conclusions

In this study, D-FIS proved to be a feasible and valid instrument for measuring MS-related fatigue, a frequent symptom associated with deterioration of patients' HRQoL.

Key Words: assessment, D-FIS, fatigue, multiple sclerosis, psychometric attributes, quality of life

First published on February 16, 2007, doi:10.1177/1352458506073528

Multiple Sclerosis 2007;13:645.

A more recent version of this article appeared on June 1, 2007

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This article has been cited by other articles:


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 Mult SclerHome page
J. Rivera-Navarro, J. Benito-Leon, C. Oreja-Guevara, J. Pardo, W. Bowakim Dib, E. Orts, M. Bello, and Caregiver Quality of Life in Multiple Sclerosis (C
Burden and health-related quality of life of Spanish caregivers of persons with multiple sclerosis
Multiple Sclerosis, November 1, 2009; 15(11): 1347 - 1355.
[Abstract] [PDF]


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