SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Multiple Sclerosis
This Article
Right arrow Full Text (OnlineFirst PDF)
Right arrow All Versions of this Article:
1352458507078392v1
13/8/996    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Kos, D.
Right arrow Articles by Kerckhofs, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kos, D.
Right arrow Articles by Kerckhofs, E.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Article

Multidisciplinary fatigue management programme in multiple sclerosis: a randomized clinical trial

Daphne Kos1*, M B D'Hooghe2, G Nagels3, M Duportail3, and Eric Kerckhofs4

1 Department of Rehabilitation Research, Vrije Universiteit Brussel, Brussels, Belgium
2 Department of Occupational Therapy, National MS Centre, Melsbroek, Belgium
3 Department of Neurology, National MS Centre, Melsbroek, Belgium
4 Department of Neurological Rehabilitation, Vrije Universiteit Brussel, Brussels, Belgium

* To whom correspondence should be addressed.


  Abstract

Objective To establish the efficacy of a multidisciplinary fatigue management programme (MFMP) in MS. Method Fifty-one subjects with MS were randomly allocated to group A, who only received the four weeks MFMP, or group B receiving a placebo intervention programme first and the MFMP after 6 months. In both groups, assessment was performed at baseline, 3 weeks and 6 months after the programmes and included Modified Fatigue Impact Scale (MFIS), Fatigue Severity Scale (FSS), MS Self-Efficacy scale (MSSE), Mental Health Inventory (MHI) and Impact on Participation and Autonomy (IPA). Results The MFIS showed a significant change over time (F(4,152)53.346, P50.012), which was similar in both groups (time*group interaction: F(4,152)51.094, P50.361). A clinically relevant reduction of MFIS score of 10 points or more was found in 17% of individuals following the MFMP, compared to 44% after the placebo intervention programme (P50.06). Compared to no intervention, a significant effect of the MFMP after 6 months (P50.003) was found in five participants (31%). No significant changes in FSS, MSSE, MHI and IPA, in both groups, were found. Conclusion Although an additional effect was found, the multidisciplinary fatigue management programme showed no efficacy in reducing the impact of fatigue compared to a placebo intervention programme. Multiple Sclerosis 2007; 13: 000-000. http://msj.sagepub.com

Key Words: education; energy management; fatigue management programme; modified fatigue impact scale; multidisciplinary; self-care

First published on July 10, 2007, doi:10.1177/1352458507078392

Multiple Sclerosis 2007;13:996.

A more recent version of this article appeared on September 1, 2007

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?




Advertisement