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First published on January 21, 2008, doi:10.1177/1352458507082724

Multiple Sclerosis 2008;14:391.

A more recent version of this article appeared on April 1, 2008
 This version was published on April 4, 2008

Article

Cross-cultural adaptation and validation of the'Multiple Sclerosis Quality of Life Instrument' in Hungarian

J Füvesi1, K Bencsik2, K. Benedek1, K Mátyás2, E. Mészáros1, C Rajda1, E. Losonczi1, Zs. Fricska-Nagy1, and Laszlo Vécsei1*

1 Department of Urology, University of Thessaly School of Medicine, Larissa, Greece
2 Department of Neurology, University of Thessaly School of Medicine, Larissa, Greece

* To whom correspondence should be addressed.


  Abstract

Health-related quality of life measurements are gaining more importance in the study and clinical practiceof multiple sclerosis. The aim of our study was the adaptation of the Multiple Sclerosis Quality ofLife Instrument (MSQOL-54) in Hungarian. The study was carried out at the Department of Neurology,University of Szeged and two other multiple sclerosis centers. The Hungarian translation of the questionnairewas given to patients at the outpatient units of the neurology departments. The EDSS scoreof the patients were determined and data concerning the onset and the clinical form of the diseasewas collected. Altogether 438 patients filled out the questionnaire. We enrolled patients with all clinicalforms of the disease. Cronbach's alpha coefficients were over 0.8 in case of all scales except 'Rolelimitations– emotional' (0.794), indicating a good internal consistency reliability for group comparisons.The instrument was able to distinguish between known clinical group differences. TheHungarian version of the MSQOL-54 instrument shows good psychometric properties similar to theoriginal questionnaire.

Key Words: health-related quality of life; internal consistency reliability; multiple sclerosis; quality oflife; validation


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