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First published on January 21, 2008, doi:10.1177/1352458507083444

Multiple Sclerosis 2008;14:415.

A more recent version of this article appeared on April 1, 2008

Article

Uveitis associated with multiple sclerosis

Pascal Sève1*, Julie Le Scanff1, Christel Renoux2, Christiane Broussolle1, Christian Confavreux2, and Sandra Vukusic2

1 Department of Internal Medicine, Hospices Civils de Lyon, Hotel Dieu, 1 place de l'Hôpital, 69288 Lyon Cedex 02,France and University Claude Bernard Lyon 1, Lyon, France
2 Department of Neurology A and EDMUS Coordinating Center, Hôpital Neurologique, Hospices Civils de Lyon, Lyon,France; INSERM U842, Lyon, France; Université Lyon 1, Lyon, France

* To whom correspondence should be addressed.


  Abstract

Our study aimed to determine the frequency of uveitis among MS patients through the Lyon MSDatabase and compare the clinical spectrum and time course of MS in patients with or withoutuveitis. Twenty-eight patients with uveitis were detected. The prevalence of uveitis in our populationwas 0.65% (28/4300). Uveitis preceded onset of MS in 46% of the patients; it occurred simultaneouslyor after MS, in 18% and 36% of the cases, respectively. The topography and timing of uveitiswere not associated with any significant difference in MS course and prognosis. There was no differencein the course and prognosis in patients with or without uveitis.

Key Words: multiple sclerosis; uveitis


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