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Multiple Sclerosis
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Brain magnetic resonance imaging findings in acute relapses of neuromyelitis optica spectrum disorders

JA Cabrera-Gómez

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba, cabrera.gomez{at}infomed.sld.cu

A. Saiz-Hinarejos

Service of Neurology Hospital Clinic and Institut d'Investigación Biomèdica August Pi i Sanyer (IAIBAPS), University of Barcelona, Villarroel 170, 08036 Barcelona, Spain

F. Graus

Service of Neurology Hospital Clinic and Institut d'Investigación Biomèdica August Pi i Sanyer (IAIBAPS), University of Barcelona, Villarroel 170, 08036 Barcelona, Spain

A. González-Quevedo

Institute of Neurology and Neurosurgery, 29 y D, Vedado, Havana, Cuba

R. Rodríguez-Rojas

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

L. Quevedo-Sotolongo

Cira Garcia Clinic, Havana, Cuba

Y. Real-González

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

D. Grass-Fernández

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

M. Cristófol-Corominas

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

ML Rodríguez-Cordero

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

MA Robinson-Agramonte

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

E. Infante-Velázquez

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

A. Cabrera-Núñez

'Dr Raúl Dorticós' School of Medicine, Cienfuegos, Cuba

C. Ugarte-Sánchez

Center of Medical and Surgical Investigations (CIMEQ), Calle 218 entre 13 y 11, Playa Havana, Cuba

J. Jordán-González

Center of Medical and Surgical Investigations (CIMEQ), Calle 218 entre 13 y 11, Playa Havana, Cuba

JE González de la Nuez

Center of Medical and Surgical Investigations (CIMEQ), Calle 218 entre 13 y 11, Playa Havana, Cuba

J. García-Lahera

Center of Medical and Surgical Investigations (CIMEQ), Calle 218 entre 13 y 11, Playa Havana, Cuba

R. Tellez

Center of Medical and Surgical Investigations (CIMEQ), Calle 218 entre 13 y 11, Playa Havana, Cuba

M. Baez-Martín

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

K. Romero-García

International Neurological Restoration Center (CIREN), Avenida 25 15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

We studied cranial magnetic resonance imaging (MRI) lesions in three women with acute attacks of recurrent longitudinally extensive transverse myelitis (r-LETM), recurrent-optic neuritis (r-ON) and r-LETM-CNS. Neuromyelitis Optica -immunoglobulin (IgG) antibody was positive in all cases. Brain MRI (1.5 Tesla) was performed according to protocol from consortium MS centre. We described the cranial lesions in brain MRI of acute relapses. These lesions were different from MS, most had an asymptomatic course which disappeared with time, protocol from consortium of MS centre criteria for brain MRI and seropositivity of NMO-IgG are useful tools for differentiate acute lesions of NMO/MS. Multiple Sclerosis 2008; 14: 248—251. http://msj.sagepub.com

Key Words: neuromyelitis optica spectrum disorders • recurrent longitudinally extensive transverse myelitis • recurrent optic neuritis

This version was published on March 1, 2008

Multiple Sclerosis, Vol. 14, No. 2, 248-251 (2008)
DOI: 10.1177/1352458507082617
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